
W E L C O M E
"Membrane proteins play key roles in human health, contributing to cellular signaling, immunity, and material exchange. Additionally, this class of proteins is a major target for commercial drug molecules. We are therefore dedicated to unveiling their hidden dynamics using single-molecule tools and molecular dynamics simulation, which could contribute to the development of effective therapeutic interventions. Specifically, our focus is on understanding how membrane proteins fold into their native structures and how they interact with other proteins and biomolecules. We are also expanding our research scope to include fields such as protein oxidative damage and proteomics."

Recent Selected Publications

Dec 2024 [Paper] [UNIST News Center - Kor] [- Eng]
Jan 2025 [Paper] [UNIST News Center - Kor] [- Eng]

May 2024 [Paper] [UNIST News Center - Kor] [- Eng]

May 2023 [Paper] [UNIST News Center - Kor] [- Eng]
News Updates
2025
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02 | Seoyoon has received an outstanding paper award for her recent work on "hidden pathway of oxidative protein damage" at the 2025 Graduate Symposium and Excellent Research Awards. Congrats!
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01 | Our collaborative work on the rational design of photosensitizers for cancer treatment has been published in Advanced Science (Link). Congratulations!
2024
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12 | A recent study by Seoyoon, Eojin, Victor, and Bhashini has been published in Nature Communications (Link). In their research, they uncovered a hidden pathway of protein damage via a novel oxygen-confined photooxidation mechanism. Congratulations on this remarkable achievement!
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05 | Bhashini's recent work as co-first author has been published in Nature Communications (Link). In this study, she was able to observe the effect of oxidative photocatalysis on membrane protein folding at single-molecule resolution. Congratulations!
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03 | Welcome, Shi Ho! We are excited to have you as our lab's Postdoc.
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02 | Duyoung's invited review paper has been published in Biochemical Society Transactions (Link), titled "Folding speeds of helical membrane proteins". Congratulations!
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02 | Seoyoon has received the best paper award for her outstanding work on "the speed limit of membrane protein folding" at the 2024 Graduate Symposium and Excellent Research Awards. Congrats!
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01 | Eojin has received an outstanding poster award for his work on "protein oxidative damage" at the 4th Biological Physics Symposium of the Korean Physical Society. Congrats!
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01 | Our invited book chapters have been published in a volume of Methods in Enzymology (Link Link), titled "Magnetic Tweezers for the Study of Protein Structure and Function". The book chapters are authored by Seoyoon, Daehyo, and Duyoung, providing step-by-step procedures for our single-molecule tweezer approach to membrane protein structural dynamics . Congratulations!
2023
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11 | Eojin has received an outstanding presentation award for his work on "protein aging" at the fall meeting of the Korean Physical Society. Congrats!
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11 | Our invited preview paper has been published in Structure (Link) as a part of the 30th anniversary special issue. Eojin and Duyoung wrote this preview, putting recent single-molecule findings on a protein folding chaperone in perspective.
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06 | Our invited review paper has been published in Journal of Molecular Biology (Link) as a part of a special issue titled "Changing Shape of Molecules and Changing Landscape of Molecular Biology". Bhashini and Duyoung wrote an extensive review on single-molecule force spectroscopy of membrane protein folding. Congratulations!
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05 | Our work on a new single-molecule method and membrane protein folding has been published in eLife (Link). In this work, Seoyoon, Daehyo, and Bhashini developed a robust magnetic tweezer method and characterized the "speed limit" of membrane protein folding. Congratulations!
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02 | Welcome Jeonghyun, another new color to the lab.
2019~2022
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2022.09 | Eojin continues his undergraduate works as a PhD student.
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2022.02 | Welcome Poornima, our new addition to the group as a PhD student.
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2021.04 | Welcome, Bhashini! We are excited to have you as a PhD student.
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2021.03 | Daehyo has just started a PhD program to further advance his undergraduate research.
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2021.02 | Victor has joined our group as a PhD student. Welcome!
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2020.01 | Razzak and Seoyoon have joined as the lab's first Postdoc and PhD student. Welcome!
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2019.10 | Duyoung's work on membrane protein folding as co-first author has been published in Science (Link). Congratulations!
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2019.10 | Our lab has officially opened at UNIST!